WUR - Wageningen University & Research

Industrial-scale penicillin simulation (IndPenSim) is a first principles mathematical model of a Penicillium chrysogenum fermentation. The simulation was developed in Matlab and is freely available to download. The development of the simulation is discussed in the paper titled "The development of an industrial-scale fed-batch fermentation simulation" currently available to download: here (Journal of Biotechnology). The paper has recently been extended which include the addition of a simulated ...

Bioindustry 4.0 is a cutting-edge initiative aspiring to shape the development of smart, sustainable biomanufacturing processes.By perfecting advanced technologies such as process sensor prototypes and computational methods, including artificial intelligence-driven digital twins, design support systems and federated learning, we aim to empower the bioindustry sector, helping to push back the boundaries of bioprocess design and operation. Our overarching aim is to make the development of bioprocesses ...