Metabolite Profiling NMR
SEEK ID: https://sandbox7.fairdomhub.org/assays/3827
Experimental assay
Projects: TDCC Integration
Investigation: Growth control of the eukaryote cell: a systems biology study in yeast
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Assay type: Experimental Assay Type
Technology type: Technology Type
Organisms: No organisms
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Created: 2nd Mar 2026 at 13:29
Last updated: 19th Mar 2026 at 08:14
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https://orcid.org/0000-0002-1279-5133
Background Cell growth underlies many key cellular and developmental processes, yet a limited number of studies have been carried out on cell-growth regulation. Comprehensive studies at the transcriptional, proteomic and metabolic levels under defined controlled conditions are currently lacking. Results Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the ...
Submitter: Katy Wolstencroft
Studies: A time course analysis of transcription response in yeast treated with r..., Study of the impact of changes in flux on the transcriptome, proteome, e...
Assays: Metabolite Profiling NMR, Second Metabolite Profiling NMR, metabolite profiling, protein expression profiling, transcription profiling
Comprehensive high-throughput analyses at the levels of mRNAs, proteins, and metabolites, and studies on gene expression patterns are required for systems biology studies of cell growth [4,26-29]. Although such comprehensive data sets are lacking, many studies have pointed to a central role for the target-of-rapamycin (TOR) signal transduction pathway in growth control. TOR is a serine/threonine kinase that has been conserved from yeasts to mammals; it integrates signals from nutrients or growth ...
Submitter: Katy Wolstencroft
Investigation: Growth control of the eukaryote cell: a systems...
Assays: Metabolite Profiling NMR, Second Metabolite Profiling NMR
